Ciprofloxacin 500mg Tablets - dr. Parker
Allergic reactions - most often occur at the injection sites, but may manifest as generalized urticaria, anaphylactic shock. Their appearance is associated with a violation of the injection technique, the use of cipro needles or their repeated use.
It leads to the breakdown of adipose tissue and the formation of a seal (lipohypertrophy) or deepening (lipoatrophy) at the site of the lesion. Weight gain - this complication is associated with an increase in the calorie content of Ciprofloxacin and an increase in appetite due to hunger when lipogenesis is stimulated by insulin.
Sodium and water retention in the body - swelling of the lower extremities, as well as an increase in blood pressure, are associated with fluid retention in the body and are temporary.
- To reduce the risk of the above pathological conditions, it is necessary to carefully choose injection sites and adhere to all the rules of insulin therapy.
- Lipodystrophy with insulin therapy.
- One of the rare complications of insulin therapy that occurs with prolonged and regular traumatization of small peripheral nerves and vessels with a needle is lipodystrophy.
- A disease state develops not only due to the administration of Ciprofloxacin drug, but also when insufficiently pure solutions are used.
Its appearance is associated with the immunological reaction of the body to poorly purified preparations of animal origin. The treatment of this problem consists in the use of small doses of injections of cipro purified hormone along the periphery of the affected areas.
Occurs when the technique of administering the drug is violated, as well as after the anabolic local action of injections. It is characterized by a cosmetic defect and impaired absorption of the drug. To prevent this pathology, you should regularly change the injection sites, and when using one area, leave a distance between punctures of cipro. Physiotherapy with phonophoresis with hydrocortisone ointment has a therapeutic effect.
If this is not possible, then prior to obtaining another insulin preparation, it is advisable to administer insulin with microdoses (less than 1 mg) of hydrocortisone mixed in a syringe.
However, it should be borne in mind that allergic reactions, especially local ones, often occur as a result of improper insulin administration: excessive trauma (too thick or blunt needle), the introduction of a very cold drug, the wrong choice of injection site, etc.
If the insulin dose is incorrectly calculated (its overestimation), insufficientWhen carbohydrates are taken, soon or 2-3 hours after the injection of simple insulin, the concentration of glucose in the blood decreases sharply and a serious condition occurs, up to hypoglycemic coma.
When using long-acting insulin preparations, hypoglycemia develops during the hours corresponding to the maximum action of the drug. In some cases, hypoglycemic conditions can occur with excessive physical stress or mental shock, excitement.
Of decisive importance for the development of hypoglycemia is not so much the level of glucose in the blood as the speed of its decrease. Thus, the first signs of hypoglycemia may appear already at a glucose level of 5.55 mmol / l (100 mg / 100 ml), if its decrease was very rapid; in other cases, with a slow decrease in glycemia, the patient may feel relatively well with a blood sugar content of about 2.78 mmol / l (50 mg / 100 ml) or even lower.
During the period of hypoglycemia, a pronounced feeling of hunger, sweating, palpitations, trembling of the hands and the whole body appear. In the future, there is inadequacy of behavior, convulsions, confusion or complete loss of consciousness. At the initial signs of hypoglycemia, the patient should eat 100 g of rolls, 3-4 pieces of sugar or drink a glass of sweet tea.
In the case of a hypoglycemic coma, the patient must immediately inject 60 ml of a 40% glucose solution into a vein. As a rule, after the first administration of glucose, consciousness is restored, but in exceptional cases, if there is no effect, the same amount of glucose is injected into the vein of the other arm after 5 minutes. A rapid effect occurs after subcutaneous administration of 1 mg of glucagon to the patient.
If the condition does not improve or even worsens, then after 4-5 minutes you should eat the same amount of sugar.
Hypoglycemic conditions are dangerous because of cipro of sudden death (especially in elderly patients with varying degrees of damage to the vessels of the heart or brain). With frequently recurring hypoglycemia, irreversible disorders of the psyche and memory develop, intelligence decreases, existing retinopathy appears or worsens, especially in the elderly.
Based on these considerations, in cases of labile diabetes, it is necessary to allow minimal glucosuria and slight hyperglycemia.
In some cases, diabetes is accompanied by conditions in which there is a decrease in tissue sensitivity to insulin, and 100-200 units of insulin or more are required to compensate for carbohydrate metabolism.
Insulin resistance develops not only as a result of a decrease in the number or affinity of insulin receptors, but also with the appearance of antibodies to receptors or insulin (immune type of resistance), as well as due to the destruction of insulin by protosolytic enzymes or binding by immune complexes.
In some cases, insulin resistance develops due to increased secretion of contra-insulin hormones, which is observed with diffuse toxic goiter, pheochromocytoma, acromegaly, and hypercortinism.